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• Kwon Sang Woo as Cha Song-ju
• Choi Ji Woo as Han Jung-suh
• Kim Tae Hee as Han Yu-ri
• Shin Hyun Joon as Han Tae-hwa

Jung Suh and Song Joo were best friends since young and shared a special bond with each other. They were always there for each other. They became closer when Jung Suh's mom passed away and Song Joo also lost his dad at a young age. Tragedy begins when Song Joo begins his studies overseas without Jung-suh and Jung Suh's dad remarries and she is now caught with a new stepmother (Mira), stepbrother (tae-hwa), and stepsister(yuri).

Yuri is envious of Jung Suh and Song Joo's relationship and tries her best to win Song Joo's affection but Song Joo has eyes only for Jung Suh. Tae Hwa develops feelings for the kind and caring Jung Suh, but Jung Suh strongly loves Song Joo and vice versa. Jung Suh and Song Joo are separated when Song Joo starts of his studies overseas first before Jung Suh joins him. But tragedy befalls them when Jung Suh gets involved in a car accident caused by Yuri and loses her memory. Jung Suh's identity is erased by Tae Hwa because he wants her all to himself and he can't let her leave him.

Five years later, tragedy occurs when Jung-suh gets into a car accident causing her to lose her memory. Together with Tae-hwa, they start anew. Song-joo is led to believe that she is dead. However, when they meet again one day, he is determined to remind her of the love they had for one another. When fate finally seemed to be on their side, Jung-suh is diagnosed with eye cancer.